Dias Daniel A, Urban Sylvia
School of Applied Sciences (Discipline of Applied Chemistry), RMIT University, Melbourne, Australia.
Nat Prod Res. 2009;23(10):925-39. doi: 10.1080/14786410802682536.
A detailed chemical and spectroscopic investigation of the terrestrial lichen Candelaria concolor has yielded several lichenic metabolites belonging to the pulvinic acid series, as well as several depside derivatives including pulvinic dilactone (1), vulpinic acid (4) and calycin (5). The chemical transformation of 1 to pulvinic acid (3) is reported for the first time, as is the conversion of atranorin (6) to 5-chloroatranorin (7) and then finally to 5,5'-dichloroatranorin (8) under very mild conditions. Also presented is the complete 1D and 2D NMR assignment for compounds 1, 3, 4, 5 and 8, including partial NMR chemical shift assignments for the unstable depside (7). Previously, these metabolites had only been partially assigned by NMR spectroscopy.
对陆地地衣双色蜡盘衣进行的详细化学和光谱研究，已得到了几种属于普尔文酸系列的地衣代谢产物，以及几种缩酚酸衍生物，包括普尔文双内酯（1）、狐衣酸（4）和卡利辛（5）。首次报道了1向普尔文酸（3）的化学转化，以及在非常温和的条件下，扁枝衣酸（6）向5-氯扁枝衣酸（7）的转化，最终再转化为5,5'-二氯扁枝衣酸（8）。还给出了化合物1、3、4、5和8完整的一维和二维核磁共振归属，包括不稳定缩酚酸（7）的部分核磁共振化学位移归属。此前，这些代谢产物仅通过核磁共振光谱进行了部分归属。
