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Pentylenetetrazol and penicillin are selective antagonists of GABA-mediated post-synaptic inhibition in cultured mammalian neurones.

作者信息

Macdonald R L, Barker J L

出版信息

Nature. 1977 Jun 23;267(5613):720-1. doi: 10.1038/267720a0.

DOI:10.1038/267720a0
PMID:195224
Abstract
摘要

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Pentylenetetrazol and penicillin are selective antagonists of GABA-mediated post-synaptic inhibition in cultured mammalian neurones.戊四氮和青霉素是培养的哺乳动物神经元中γ-氨基丁酸(GABA)介导的突触后抑制的选择性拮抗剂。
Nature. 1977 Jun 23;267(5613):720-1. doi: 10.1038/267720a0.
2
Specific antagonism of GABA-mediated postsynaptic inhibition in cultured mammalian spinal cord neurons: a common mode of convulsant action.培养的哺乳动物脊髓神经元中γ-氨基丁酸(GABA)介导的突触后抑制的特异性拮抗作用:惊厥作用的一种常见模式。
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3
Depolarization of dorsal root ganglia in the cat by GABA and related amino acids: antagonism by picrotoxin and bicuculline.γ-氨基丁酸及相关氨基酸对猫背根神经节的去极化作用:印防己毒素和荷包牡丹碱的拮抗作用
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4
Penicillin and inhibition in the cat spinal cord.青霉素与猫脊髓中的抑制作用
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Common synaptic effects of pentylenetetrazol and penicillin.戊四氮和青霉素的常见突触效应。
Brain Res. 1974 May 31;72(1):168-71. doi: 10.1016/0006-8993(74)90662-3.
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Pentylenetetrazol: an antagonist of GABA at primary afferents of the isolated frog spinal cord.戊四氮:离体青蛙脊髓初级传入神经上γ-氨基丁酸的拮抗剂。
Neuropharmacology. 1976 Jan;15(1):69-71. doi: 10.1016/0028-3908(76)90099-x.
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Influence of GABA and glycine and their antagonists on inhibitory mechanisms of pigeon's optic tectum.γ-氨基丁酸(GABA)和甘氨酸及其拮抗剂对鸽视顶盖抑制机制的影响。
Brain Res. 1974 Nov 22;80(3):532-7. doi: 10.1016/0006-8993(74)91039-7.
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The pharmacology and ionic dependency of amino acid responses in the frog spinal cord.青蛙脊髓中氨基酸反应的药理学及离子依赖性
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Antagonism between strychnine and glycine, and bicuculline and GABA, in the ventromedial hypothalamus.
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2-Amine 4-pentenoic acid (allylglycine): a proposed tool for the study of GABA mediated systems.2-氨基-4-戊烯酸(烯丙基甘氨酸):一种用于研究γ-氨基丁酸(GABA)介导系统的潜在工具。
Int J Neurosci. 1971 Sep;2(3):137-44. doi: 10.3109/00207457109148766.

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