Horner J, Buoyer F G, Alberts M J, Helms M J
Department of Surgery, Duke University Medical Center, Durham, NC 27710.
Arch Neurol. 1991 Nov;48(11):1170-3. doi: 10.1001/archneur.1991.00530230078026.
We studied 23 individuals (16 men, seven women; mean age 57 years) who had brainstem strokes confirmed by computed tomography of the head or magnetic resonance imaging. Videofluoroscopic modified barium-swallowing examination showed aspiration in 15 of 23 patients. Of the 15 aspirating patients, the majority had bilateral strokes with multiple lesion loci, most often in association with large-vessel disease. All 15 patients had involvement of the pons or medulla. Statistical analyses revealed a significant association between aspiration and pharyngeal residue observed under videofluoroscopy, cranial nerve IX abnormality, vocal fold weakness, and severe dysarthria. Despite initial severity, recovery was good. Following an aggressive program of aspiration prevention, over 80% of patients resumed full oral nutrition at the last follow-up.
我们研究了23名个体（16名男性，7名女性；平均年龄57岁），这些个体经头部计算机断层扫描或磁共振成像证实患有脑干中风。电视荧光透视改良吞钡检查显示，23名患者中有15名存在误吸。在这15名误吸患者中，大多数为双侧中风且有多个病变部位，最常见于合并大血管疾病时。所有15名患者均累及脑桥或延髓。统计分析显示，电视荧光透视观察到的误吸与咽部残留、第九对脑神经异常、声带麻痹及严重构音障碍之间存在显著关联。尽管初始病情严重，但恢复情况良好。经过积极的误吸预防方案，超过80%的患者在最后一次随访时恢复了完全经口营养。
