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用高剂量火鸡球虫反复接种的白来航鸡对柔嫩艾美耳球虫和堆型艾美耳球虫保护性免疫的发育

Development of protective immunity against Eimeria tenella and E. acervulina in White Leghorn chickens inoculated repeatedly with high doses of turkey coccidia.

作者信息

Augustine P C, Danforth H D, Barta J R

机构信息

U.S. Department of Agriculture, Livestock and Poultry Science Institute, Beltsville, Maryland 20705.

出版信息

Avian Dis. 1991 Jul-Sep;35(3):535-41.

PMID:1953577
Abstract

Repeated inoculation (immunization) of 2-week-old white leghorn chickens with 10(6) oocysts of the turkey coccidia Eimeria adenoeides or E. meleagrimitis partially protected chickens against moderate challenge with E. tenella or E. acervulina oocysts, but not with E. necatrix oocysts. After challenge, mean weight gains of the immunized chickens and the unchallenged controls did not differ significantly, but weight gains of unimmunized chickens were significantly lower. The mean feed-conversion ratio of the immunized challenged chickens was 3.14, as compared with 4.42 for unimmunized challenged control chickens. In general, immunization did not markedly reduce intestinal lesions. Repeated inoculation of chickens with the turkey coccidium E. gallopavonis failed to produce statistically significant protection against challenge with E. tenella, E. acervulina, or E. necatrix, as determined by weight gain, feed-conversion efficiency, and lesion scores. Antibody profiles of individual chickens did not correlate with protection.

摘要

用10⁶个火鸡球虫艾美耳球虫腺状艾美耳球虫或火鸡艾美耳球虫对2周龄的白来航鸡进行重复接种(免疫),可使鸡对柔嫩艾美耳球虫或堆型艾美耳球虫卵囊的中度攻击产生部分保护,但对毒害艾美耳球虫卵囊无效。攻击后,免疫鸡和未受攻击对照鸡的平均体重增加无显著差异,但未免疫鸡的体重增加显著较低。免疫攻击鸡的平均饲料转化率为3.14,而未免疫攻击对照鸡为4.42。一般来说,免疫并未显著减少肠道病变。用火鸡球虫火鸡艾美耳球虫对鸡进行重复接种,根据体重增加、饲料转化效率和病变评分,未能对柔嫩艾美耳球虫、堆型艾美耳球虫或毒害艾美耳球虫的攻击产生统计学上显著的保护作用。个体鸡的抗体谱与保护作用无关。

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