Isobe T, Suzuki K, Yoshihara S
Poultry Disease Laboratory, National Institute of Animal Health, Gifu, Japan.
Avian Dis. 1991 Jul-Sep;35(3):559-62.
Protection against chicken leucocytozoonosis was assessed in chickens immunized with spleen homogenates from chickens that had received sporozoites of Leucocytozoon caulleryi 7 or 13 days previously. Chickens immunized with the homogenate were challenged with sporozoites of L. caulleryi and observed for changes in clinical signs, parasitemia, serum-soluble antigen, and antibody responses. In chickens immunized with either the 7-day or 13-day homogenate, clinical signs and parasitemia were moderate, mild or absent. This was the case both after immunization with the homogenate and after sporozoite challenge. Immunization with spleen homogenates demonstrated protection against chicken leucocytozoonosis.
用7天或13天前接种了卡氏住白细胞虫子孢子的鸡的脾脏匀浆免疫鸡，评估其对鸡住白细胞虫病的保护作用。用该匀浆免疫的鸡用卡氏住白细胞虫子孢子进行攻毒，并观察其临床症状、虫血症、血清可溶性抗原和抗体反应的变化。用7天或13天的匀浆免疫的鸡，临床症状和虫血症为中度、轻度或无。在匀浆免疫后和子孢子攻毒后均是如此。用脾脏匀浆免疫显示对鸡住白细胞虫病有保护作用。
