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脉冲电磁场对大鼠胫骨实验性骨不连愈合的影响。

Effect of pulsed electromagnetic field on healing of experimental nonunion in rat tibiae.

作者信息

Muhsin A U, Islam K M, Ahmed A M, Islam M S, Rabbani K S, Rahman S M, Ahmed S, Hossain M

机构信息

IPGMR, Dhaka University.

出版信息

Bangladesh Med Res Counc Bull. 1991 Jun;17(1):1-10.

PMID:1953591
Abstract

To see the effect of Pulsed Electromagnetic Field (PEMF) on nonunited fracture healing, nonunion was induced in rat tibiae and PEMF was applied on it. Out of five different techniques utilised for inducing nonunion soft tissue interposition was found to be the most suitable and effective method of experimental induction of nonunion. Twenty eight experimental and 15 control rats were finally evaluated for the effect of PEMF applied for up to 8 weeks. After sacrifice of 8 experimental and 4 controls, 6 experimental and 3 controls, again 6 experimental and 3 controls and finally 8 experimental and 5 controls at 2, 4, 6 and 8 weeks respectively of PEMF application no significant difference as to the quality of healing was observed between the experimental and control animals. It was thus concluded that PEMF appeared to have no beneficial effect on the healing of nonunited fractures in experimental set-up.

摘要

为观察脉冲电磁场(PEMF)对骨折不愈合的影响,在大鼠胫骨上造成骨折不愈合,并对其施加PEMF。在用于诱导骨折不愈合的五种不同技术中,发现软组织嵌入是实验性诱导骨折不愈合最适宜且有效的方法。最终对28只实验大鼠和15只对照大鼠进行评估,观察施加PEMF长达8周的效果。在分别施加PEMF 2周、4周、6周和8周后,依次处死8只实验大鼠和4只对照大鼠、6只实验大鼠和3只对照大鼠、再6只实验大鼠和3只对照大鼠,最后8只实验大鼠和5只对照大鼠,结果发现实验大鼠和对照动物在愈合质量上没有显著差异。因此得出结论,在实验条件下,PEMF似乎对骨折不愈合的愈合没有有益作用。

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