Lee Hwansung, Ikeuchi Yoshiaki, Akagawa Eiki, Tatsumi Eisuke, Taenaka Yoshiyuki, Yamamoto Takao
Department of Artificial Organs, Research Institute, National Cardiovascular Center, Suita, Osaka, Japan.
J Artif Organs. 2009;12(2):98-104. doi: 10.1007/s10047-009-0453-8. Epub 2009 Jun 18.
Our group is currently developing a pneumatic ventricular assist device (PVAD). In this study, in order to select the optimal bileaflet valve for our PVAD, three kinds of bileaflet valve were installed and the flow was visualized downstream of the outlet valve using the particle image velocimetry (PIV) method. To carry out flow visualization inside the blood pump and near the valve, we designed a model pump that had the same configuration as our PVAD. The three bileaflet valves tested were a 21-mm ATS valve, a 21-mm St. Jude valve, and a 21-mm Sorin Bicarbon valve. The mechanical heart valves were mounted at the aortic position of the model pump and the flow was visualized by using the PIV method. The maximum flow velocity was measured at three distances (0, 10, and 30 mm) from the valve plane. The maximum flow velocity of the Sorin Bicarbon valve was less than that of the other two valves; however, it decreased slightly with increasing distance it the X-Y plane in all three valves. Although different bileaflet valves are very similar in design, the geometry of the leaflet is an important factor when selecting a mechanical heart valve for use in an artificial heart.
我们的团队目前正在研发一种气动心室辅助装置（PVAD）。在本研究中，为了为我们的PVAD选择最佳的双叶瓣瓣膜，安装了三种双叶瓣瓣膜，并使用粒子图像测速（PIV）方法在出口瓣膜下游对血流进行可视化。为了在血泵内部和瓣膜附近进行血流可视化，我们设计了一个与我们的PVAD具有相同结构的模型泵。测试的三种双叶瓣瓣膜分别是一个21毫米的ATS瓣膜、一个21毫米的圣犹达瓣膜和一个21毫米的索林·碳酸氢盐瓣膜。将机械心脏瓣膜安装在模型泵的主动脉位置，并使用PIV方法对血流进行可视化。在距瓣膜平面三个距离（0、10和30毫米）处测量最大流速。索林·碳酸氢盐瓣膜的最大流速低于其他两种瓣膜；然而，在所有三种瓣膜中，其在X-Y平面内随距离增加而略有下降。尽管不同的双叶瓣瓣膜在设计上非常相似，但在为人工心脏选择机械心脏瓣膜时，瓣叶的几何形状是一个重要因素。
