Ares Valdés Yolanda
Servicio de Urología, Hospital Universitario Manuel Fajardo, Ciudad Habana, Cuba.
Arch Esp Urol. 2009 Apr;62(3):201-6. doi: 10.4321/s0004-06142009000300005.
To evaluate the correlation between type of presentation in patients with renal cell carcinoma and survival.
Longitudinal retrospective study of 42 patients with clinical and histological diagnosis of renal cell carcinoma (RCC) between July 2002 and September 2007 at University Hospital Manuel Fajardo. The following variables were studied: Sex, age, clinical presentation: 1) asymptomatic: 2) symptomatic: 3) paraneoplastic syndrome; tumor stage (TNM 1997) and survival.
There is a predominance of men over women, the age of greater incidence was between the fifth a and seventh decades. The tumors were classified as: asymptomatic 7%, 3/42; symptomatic 67%, 28/42, with flank pain 31%, 13/42; with hematuria 24%, 10/42, and tumor 10%, 4/42, the classic triad of hematuria, flank pain and mass was 2.3%, 1/42 of the patients and paraneoplastic syndrome 24%, 11/42. The patients with non-metastatic disease were 57%, 24/42 and 43%, 18/42 presented metastases. Five-year survival for patients with RCC by TNM stage was T1, 100% ( 12/12) , T2, 97% (11/12) , T3, 36% (4/11) , T4, 0% (0/7) . The survival of localized and metastatic RCC was 95%, 23/24 and 22%, 4/18 cases respectively and all stage was 64% (27/42).
The asymptomatic RCCs were smaller; pain, hematuria, and mass were the most common manifestations in symptomatic RCC. The prognosis is dismal in patients with RCC showing paraneoplastic syndromes.
评估肾细胞癌患者的临床表现类型与生存率之间的相关性。
对2002年7月至2007年9月在曼努埃尔·法哈多大学医院临床和组织学诊断为肾细胞癌（RCC）的42例患者进行纵向回顾性研究。研究了以下变量：性别、年龄、临床表现：1）无症状；2）有症状；3）副肿瘤综合征；肿瘤分期（TNM 1997）和生存率。
男性多于女性，发病率最高的年龄在五到七十岁之间。肿瘤分类如下：无症状7%，3/42；有症状67%，28/42，其中胁腹痛31%，13/42；血尿24%，10/42，肿物10%，4/42，血尿、胁腹痛和肿物的经典三联征占患者的2.3%，1/42，副肿瘤综合征24%，11/42。非转移性疾病患者占57%，24/42，43%，18/42有转移。根据TNM分期，RCC患者的五年生存率为：T1期100%（12/12），T2期97%（11/12），T3期36%（4/11），T4期0%（0/7）。局限性和转移性RCC的生存率分别为95%，23/24和22%，4/18例，所有分期的生存率为64%（27/42）。
无症状RCC体积较小；疼痛、血尿和肿物是有症状RCC最常见的表现。表现出副肿瘤综合征的RCC患者预后不佳。
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