Bernabeu A, Iniesta A, Martín Luengo F
Departamento de Genética y Microbiología, Facultad de Medicina, Murcia.
Enferm Infecc Microbiol Clin. 1991 May;9(5):289-91.
We studied the possible relationship between the presence of bacteriophages and cytotoxicity of Clostridium difficile strains from multiple origin. A total of 143 strains were studied, 38.46% showed lysogenic activity to at least one of control strains and 85.3% produces cytopathic effects on McCoy cells, that were neutralized by C. sordellii antitoxin. All bacteriophages seen on electron microscopy showed similar shape and size (hexagonal head shape and flexible tail ended in a basal plate). According to our results, a significant relationship between those two factors seems not to exist.
我们研究了来自多个来源的艰难梭菌菌株中噬菌体的存在与细胞毒性之间的可能关系。共研究了143株菌株，38.46%对至少一种对照菌株表现出溶原活性，85.3%对 McCoy 细胞产生细胞病变效应，这些效应可被索氏梭菌抗毒素中和。电子显微镜下观察到的所有噬菌体均呈现相似的形状和大小（六边形头部形状，柔性尾部末端有基板）。根据我们的结果，这两个因素之间似乎不存在显著关系。
