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眉部的疣状斑块。

A verrucous plaque of the eyebrow.

作者信息

Kerchner Katherine R, Swing Donald C, Williford Phillip R

机构信息

Department of Dermatology, Wake Forest University Baptist Medical Center, Winston-Salem, NC, USA.

出版信息

Am J Dermatopathol. 2009 Jul;31(5):506-8. doi: 10.1097/DAD.0b013e3181877a1f.

Abstract

Phaeohyphomycosis is a rare dematiaceous fungal infection requiring surgical excision or appropriate systemic antifungal therapy. The objective of this study is to report a case of phaeohyphomycosis of the right eyebrow successfully treated with surgical excision. We performed an excision of a dermal plaque of phaeohyphomycosis using 4-mm margins on the right brow extending onto the right forehead. An island pedicle flap was used to close the defect. Histopathologic evaluation confirmed the presence of numerous dematiaceous fungal organisms fully consistent with phaeohyphomycosis, and the margins were verified to be free of fungal organisms. Culture of a central portion of the excised lesion confirmed that the causative organism was a saprophytic fungus. Adjuvant systemic antifungal therapy was offered to the patient, but because of financial resources, the patient did not desire any further treatment. The patient remains free of the organism and has healed well, without complications. Phaeohyphomycosis can be effectively treated with excision alone, and when located in a risky anatomic location, such as near the orbit, adjuvant treatment with systemic antifungals may be warranted to prevent recurrence.

摘要

暗色丝孢霉病是一种罕见的暗色真菌感染,需要手术切除或适当的全身抗真菌治疗。本研究的目的是报告一例通过手术切除成功治疗的右眉暗色丝孢霉病病例。我们对右眉延伸至右前额的暗色丝孢霉病皮肤斑块进行了切除,切缘为4毫米。采用岛状蒂皮瓣关闭缺损。组织病理学评估证实存在大量与暗色丝孢霉病完全一致的暗色真菌,且切缘经证实无真菌。对切除病变中央部分的培养证实病原体是一种腐生真菌。我们向患者提供了辅助全身抗真菌治疗,但由于经济原因,患者不希望进一步治疗。患者体内已无该病原体,愈合良好,无并发症。暗色丝孢霉病单独通过切除即可有效治疗,当位于眼眶附近等危险解剖部位时,可能需要辅助全身抗真菌治疗以预防复发。

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