Maudgil A, Johnson Z, Rogers N, Mudhar H S
Department of Ophthalmology, Royal Hallamshire Hospital, Sheffield, UK.
Department of Ophthalmology, Newcastle Eye Centre, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Royal Victoria Infirmary, Newcastle upon Tyne, UK.
Eye (Lond). 2016 Nov;30(11):1517-1519. doi: 10.1038/eye.2016.155. Epub 2016 Jul 22.
PurposePhaeohyphomycosis are melanin-containing fungi that rarely infect the eye. We describe three cases of ocular infection with some unusual clinical features.MethodsSeries of three case reports describing three different presentations of phaeohyphomycosis of the eye, their histopathology, and management.ResultsCase 1 mimicked an inflamed conjunctival naevus and was excised on this basis, revealing a conjunctival retention cyst containing pigmented fungal hyphae. Case 2 showed a wooden foreign body incidentally associated with pigmented fungal hyphae, which required treatment with topical antifungal therapy. Case 3 clinically was thought to be a perforated uveal melanoma and comprised an extensive plaque of pigmented fungal hyphae over ulcerated cornea.ConclusionThe pigmented melanin containing hyphae of phaeohyphomycosis mimicked melanocytic lesions in two cases and was an incidental finding in the context of a surface foreign body.
目的
暗色丝孢霉病是一种含有黑色素的真菌，很少感染眼部。我们描述了三例具有一些不寻常临床特征的眼部感染病例。
方法
系列三例病例报告，描述了眼部暗色丝孢霉病的三种不同表现、组织病理学及治疗方法。
结果
病例1类似发炎的结膜痣并在此基础上进行了切除，结果显示为一个含有色素真菌菌丝的结膜潴留囊肿。病例2显示一个木质异物偶然与色素真菌菌丝相关，需要局部抗真菌治疗。病例3临床上被认为是穿孔性葡萄膜黑色素瘤，在溃疡的角膜上有一大片色素真菌菌丝斑。
结论
暗色丝孢霉病含色素的黑色素菌丝在两例中类似黑素细胞病变，在表面异物情况下为偶然发现。
