Kala Z, Weber P, Marek F, Procházka V, Meluzínová H, Dolina J, Kroupa R, Hep A
Faculty Hospital Brno, Department of Surgery, Brno, Czech Republic.
Z Gerontol Geriatr. 2009 Oct;42(5):408-11. doi: 10.1007/s00391-008-0013-5. Epub 2009 Jun 20.
Achalasia is an uncommon illness affecting 1 per 100,000 patients a year. It encompasses a rare, primary motor disorder of the distal esophagus.
Over the period 1998-2006, 115 patients underwent various treatments for achalasia; the subgroup of seniors consisted of 26 patients. Six patients of these (age 69.7 y) underwent a modified Heller cardiomyotomy due to failure of previous endoscopic interventions. Standard esophageal manometry and 24 hour pH metry were performed pre- and postoperatively.
Six senior patients with achalasia underwent a laparoscopic Heller myotomy. Average preoperative tonus of the LES was 55 mmHg, postoperative tonus of the LES decreased to 11 mmHg. We performed Toupet partial fundoplication in all patients; no microperforation of the esophagus was found in the preoperative esophagoscopy. We recorded minimal pathological gastroesophageal reflux in pH metry - the average preoperative DeMeester score was 8, postoperatively 10.5. Prolonged dysphagia was not present in any patient--preoperative GIQLI score was 94, postoperative score was 106. There was no mortality or morbidity in the group of the operated patients.
Our operational results and postoperative follow-up show that laparoscopic Heller myotomy with Toupet partial fundoplication is a safe and effective treatment and can be recommended as the method of first choice for senior patients with no contraindication for laparoscopic operation.
贲门失弛缓症是一种罕见疾病,每年发病率为十万分之一。它是一种罕见的原发性食管远端运动障碍疾病。
1998年至2006年期间,115例贲门失弛缓症患者接受了各种治疗;老年亚组包括26例患者。其中6例患者(年龄69.7岁)因先前内镜干预失败而接受了改良的Heller贲门肌切开术。术前和术后均进行了标准食管测压和24小时pH监测。
6例老年贲门失弛缓症患者接受了腹腔镜Heller肌切开术。术前LES平均张力为55mmHg,术后LES张力降至11mmHg。所有患者均进行了Toupet部分胃底折叠术;术前食管镜检查未发现食管微穿孔。pH监测记录到最小病理性胃食管反流——术前平均DeMeester评分为8,术后为10.5。所有患者均未出现持续性吞咽困难——术前GIQLI评分为94,术后评分为106。手术患者组无死亡或并发症发生。
我们的手术结果和术后随访表明,腹腔镜Heller肌切开术联合Toupet部分胃底折叠术是一种安全有效的治疗方法,可推荐作为无腹腔镜手术禁忌证的老年患者的首选治疗方法。