Létourneau Daniel, Publicover Julia, Kozelka Jakub, Moseley Douglas J, Jaffray David A
Radiation Medicine Program, Princess Margaret Hospital, Toronto, Ontario M5G 2M9, Canada.
Med Phys. 2009 May;36(5):1813-21. doi: 10.1118/1.3117563.
The objective of this work is to assess the suitability and performance of a new dosimeter system with a novel geometry for the quality assurance (QA) of volumetric modulated arc therapy (VMAT). The new dosimeter system consists of a hollow cylinder (15 and 25 cm inner and outer diameters) with 124 diodes embedded in the phantom's cylindrical wall forming four rings of detectors. For coplanar beams, the cylindrical geometry and the ring diode pattern offer the advantage of invariant perpendicular incidence on the beam central axis for any gantry angle and also have the benefit of increasing the detector density as both walls of the cylinder sample the beam. Other advantages include real-time readout and reduced weight with the hollow phantom shape. A calibration method taking into account the variation in radiation sensitivity of the diodes as a function of gantry angle was developed and implemented. In this work, the new dosimeter system was used in integrating mode to perform composite dose measurements along the cylindrical surface supporting the diodes. The reproducibility of the dosimeter response and the angular dependence of the diodes were assessed using simple 6 MV photon static beams. The performance of the new dosimeter system for VMAT QA was then evaluated using VMAT plans designed for a head and neck, an abdominal sarcoma, and a prostate patient. These plans were optimized with 90 control points (CPs) and additional versions of each plan were generated by increasing the number of CPs to 180 and 360 using linear interpolation. The relative dose measured with the dosimeter system for the VMAT plans was compared to the corresponding TPS dose map in terms of relative dose difference (% deltaD) and distance to agreement (DTA). The dosimeter system's sensitivity to gantry rotation offset and scaling errors as well as setup errors was also evaluated. For static beams, the dosimeter system offered good reproducibility and demonstrated small residual diode angular dependence after calibration. For VMAT deliveries, the agreement between measured and calculated doses was good with > or = 86.4% of the diodes satisfying 3% of % deltaD or 2 mm DTA for the 180 CP plans. The phantom offered sufficient sensitivity for the detection of small gantry rotation offset (3 degrees) and scaling errors (1 degree) as well as phantom setup errors of 1 mm, although the results were plan dependent. With its novel geometry, the dosimeter system was also able to experimentally demonstrate the discretization effect of the number of CPs used in the TPS to simulate a continuous arc. These results demonstrate the suitability of the new dosimeter system for the patient-specific QA of VMAT plans and suggest that the dosimeter system can be an effective tool in the routine QA and commissioning of treatment machines capable of VMAT delivery and cone-beam CT image guidance.
这项工作的目的是评估一种具有新型几何结构的新剂量计系统对于容积调强弧形治疗(VMAT)质量保证(QA)的适用性和性能。新剂量计系统由一个空心圆柱体(内径15 cm,外径25 cm)组成,在体模的圆柱壁中嵌入了124个二极管,形成四个探测器环。对于共面射束,圆柱几何结构和环形二极管模式具有以下优势:对于任何机架角度,在射束中心轴上具有不变的垂直入射,并且由于圆柱体的两个壁都对射束进行采样,还具有增加探测器密度的优点。其他优点包括实时读出以及空心体模形状带来的重量减轻。开发并实施了一种校准方法,该方法考虑了二极管辐射灵敏度随机架角度的变化。在这项工作中,新剂量计系统以积分模式用于沿支撑二极管的圆柱表面进行复合剂量测量。使用简单的6 MV光子静态射束评估了剂量计响应的可重复性和二极管的角度依赖性。然后,使用为头颈部、腹部肉瘤和前列腺患者设计的VMAT计划评估新剂量计系统用于VMAT QA的性能。这些计划用90个控制点(CP)进行了优化,并且通过使用线性插值将CP数量增加到180和360生成了每个计划的其他版本。将剂量计系统为VMAT计划测量的相对剂量与相应的治疗计划系统(TPS)剂量图在相对剂量差异(% deltaD)和距离一致性(DTA)方面进行了比较。还评估了剂量计系统对机架旋转偏移和缩放误差以及设置误差的敏感性。对于静态射束,剂量计系统具有良好的可重复性,并且在校准后显示出较小的二极管残余角度依赖性。对于VMAT照射,测量剂量与计算剂量之间的一致性良好,对于180个CP的计划,≥86.4%的二极管满足3%的% deltaD或2 mm的DTA。尽管结果与计划有关,但该体模对于检测小的机架旋转偏移(3度)和缩放误差(1度)以及1 mm的体模设置误差具有足够的灵敏度。凭借其新颖的几何结构,剂量计系统还能够通过实验证明TPS中用于模拟连续弧形的CP数量的离散化效应。这些结果证明了新剂量计系统对于VMAT计划的患者特异性QA的适用性,并表明该剂量计系统可以成为能够进行VMAT照射和锥束CT图像引导的治疗机器的常规QA和调试中的有效工具。