百日咳博德特氏菌表面暴露的可被抗体识别的外膜蛋白

Surface-exposed antibody-accessible outer membrane proteins of Bordetella pertussis.

作者信息

Anwar H

机构信息

Department of Microbiology, University of Alberta, Edmonton, Alta., Canada.

出版信息

Can J Microbiol. 1991 Aug;37(8):590-3. doi: 10.1139/m91-100.

DOI:10.1139/m91-100

PMID:1954571

Abstract

The convalescent sera from a patient recovered from whooping cough were used to identify the surface-exposed antibody-accessible outer membrane proteins (OMPs) of Bordetella pertussis. The results indicated that the 69,000 OMP, the 40,000 porin, agglutinogens 2 and 3, and a number of presently unknown OMPs were exposed on the surface. The importance of these surface-exposed antigens in the protection against whooping cough is discussed.

摘要

从一名百日咳康复患者身上获取的恢复期血清，被用于鉴定百日咳博德特氏菌表面暴露的、抗体可及的外膜蛋白（OMPs）。结果表明，69000的OMP、40000的孔蛋白、凝集原2和3以及一些目前未知的OMPs暴露于表面。文中讨论了这些表面暴露抗原在预防百日咳中的重要性。