Betts R F, Freeman R B, Douglas R G, Talley T E
Am J Dis Child. 1977 Jul;131(7):759-63. doi: 10.1001/archpedi.1977.02120200041010.
Seventy seven patients, thirteen younger than 20 years of age, were followed up prospectively for the first three months after renal transplant for evidence of infection and illness due to cytomegalovirus (CMV). Thirty-two developed reactivation of latent CMV and 29 did not develop any CMV infection and wn, five had pneumonia, and four underwent nephrectomy. Of these, 16, eleven received a kidney from a parent, whereas of the other 61 patients, five received parental kidneys (P less than .001). Hence, CMV seronegative individuals who received a kidney from a CMV seropositive parent developed clinical illness and sometimes lost the allograft.
77例患者（其中13例年龄小于20岁）在肾移植后的前三个月接受了前瞻性随访，以寻找巨细胞病毒（CMV）感染及相关疾病的证据。32例出现潜伏CMV再激活，29例未发生任何CMV感染，5例发生肺炎，4例行肾切除术。其中16例（11例接受来自父母的肾脏），而在其他61例患者中，5例接受父母的肾脏（P<0.001）。因此，从CMV血清学阳性的父母处接受肾脏的CMV血清学阴性个体出现了临床疾病，有时还失去了移植肾。
