Department of Pulmonary and Critical Care Medicine, Respiratory Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
Respiration. 2010;79(1):77-80. doi: 10.1159/000226133. Epub 2009 Jun 23.
Although small cell cancer of the lung may have protean manifestations, tumor embolization and inability to identify the primary sites are unusual features. We present a patient with anti-Hu antibody-associated paraneoplastic sensory polyneuropathy and tumor embolism diagnosed by endovascular biopsy to be due to small cell cancer, the primary site of which was not evident. To our knowledge, this patient represents only the second individual to be described with tumor embolization complicating small cell cancer and reminds clinicians of the extended spectrum of this disease.
虽然小细胞肺癌可能有多种表现,但肿瘤栓塞和无法确定原发灶是不常见的特征。我们报告了一例抗 Hu 抗体相关副肿瘤感觉性多神经病和肿瘤栓塞的患者,通过血管内活检诊断为小细胞癌,但其原发灶不明显。据我们所知,该患者是第二位描述肿瘤栓塞合并小细胞癌的患者,这提醒临床医生注意该疾病的广泛谱。