Yap Alan K W, Klineberg Iven
Faculty of Dentistry, University of Sydney, Professorial Unit, Sydney, Australia.
Int J Prosthodont. 2009 May-Jun;22(3):268-76.
The aims of this article are to critique the available literature on dental implants in patients with ectodermal dysplasia (ED) syndrome and tooth agenesis, review the outcomes of implant therapy in these patients, and provide recommendations on the timing of implant placement for these patients.
Searches were performed using Medline, Embase, All EBM Reviews, and Pre-Medline for articles relating to implant patients suffering from ED. Articles unrelated to the topic of dental implants in patients with ED and tooth agenesis, without abstracts, or in languages other than English were excluded. Selected articles were graded according to levels of evidence based upon guidelines set forth by the Agency for Health Care Policy and Research. Articles found to have a level of evidence of IV were excluded from this study.
The literature on dental implants in patients with ED and tooth agenesis was found to be scarce. No randomized controlled or case-controlled studies were found. Only 12 articles were found to satisfy all inclusion criteria.
Implant survival rates vary between 88.5% and 97.6% in patients with ED and between 90% and 100% in patients with tooth agenesis. Implants placed in adolescent ED patients do not have a significant effect on craniofacial growth, while implants placed in ED patients younger than 18 years have a higher risk of failure.
本文旨在对有关外胚层发育不全（ED）综合征和牙齿发育不全患者牙种植体的现有文献进行批判性分析，回顾这些患者种植治疗的结果，并为这些患者种植体植入的时机提供建议。
使用Medline、Embase、所有循证医学综述和预Medline检索与患有ED的种植患者相关的文章。排除与ED和牙齿发育不全患者牙种植体主题无关、无摘要或非英语语言的文章。根据卫生保健政策与研究机构制定的指南，对所选文章按照证据水平进行分级。本研究排除证据水平为IV级的文章。
发现关于ED和牙齿发育不全患者牙种植体的文献很少。未找到随机对照或病例对照研究。仅发现1篇符合所有纳入标准的文章。
ED患者的种植体存活率在88.5%至97.6%之间，牙齿发育不全患者的种植体存活率在90%至100%之间。在青少年ED患者中植入种植体对颅面生长无显著影响，而在18岁以下的ED患者中植入种植体失败风险较高。
