Department of Dermatology, Deventer Hospital, Deventer, The Netherlands.
Clin Exp Dermatol. 2010 Jan;35(1):36-40. doi: 10.1111/j.1365-2230.2009.03377.x. Epub 2009 Jun 22.
Hidradenitis suppurativa (HS) is a chronic, inflammatory skin disease characterized by abscess formation localized to apocrine sweat gland-bearing skin. The most important factor in patients' overall assessment of disease severity is pain. The duration of abscesses takes days to weeks and are always painful.
To assess the efficacy of self-treatment with topical 15% resorcinol in an open study.
The case notes of 12 women with stage 1 or 2 HS treated with topical resorcinol and followed up for at least 1 year were reviewed. The patients rated the efficacy of treatment on global maximum pain of nodules and abscesses on a visual analogue scale (VAS) and by self-report of the mean duration (days) of a painful lesion.
All patients experienced a significant decrease in pain as assessed by VAS and reported a reduction in mean duration of the painful abscesses.
Topical treatment with 15% resorcinol reduced pain from painful nodules in all patients with HS. Further trials are warranted to confirm these results.
化脓性汗腺炎（HS）是一种慢性炎症性皮肤病，其特征为在顶泌汗腺分布区域形成脓肿。在患者对疾病严重程度的整体评估中，最重要的因素是疼痛。脓肿的持续时间为数天到数周，并且始终伴有疼痛。
评估局部使用 15%间苯二酚进行自我治疗的疗效，这是一项开放性研究。
对 12 名患有 1 期或 2 期化脓性汗腺炎的女性患者的病历进行了回顾，这些患者接受了间苯二酚治疗，并至少随访了 1 年。患者通过视觉模拟评分（VAS）评估结节和脓肿的最大疼痛程度，以及自我报告疼痛病变的平均持续时间（天数）来评估治疗效果。
所有患者的 VAS 评估疼痛均显著减轻，并且报告疼痛脓肿的平均持续时间缩短。
局部使用 15%间苯二酚治疗可减轻所有化脓性汗腺炎患者的疼痛性结节疼痛。需要进一步的试验来证实这些结果。
