van Thiel R J, van der Burg S, Groote A D, Nossent G D, Wills S H
Dept. of Pulmonary Diseases, Diakonessenhuis Groningen, The Netherlands.
Eur Respir J. 1991 Jul;4(7):905-11.
Bronchiolitis obliterans, with or without organizing pneumonia, can be a serious and life-threatening complication of rheumatoid arthritis. We describe a case of bronchiolitis obliterans organizing pneumonia in a patient who recently developed rheumatoid arthritis, presenting as a severe respiratory insufficiency. Diagnosis was made by means of open lung biopsy. Treatment with corticosteroids induced a quick response and substantial improvement of the respiratory symptoms. A simultaneous strong rise in titres of serological tests suggests a relationship between the bronchiolitis obliterans organizing pneumonia and the rheumatoid arthritis.
闭塞性细支气管炎，伴或不伴有机化性肺炎，可能是类风湿关节炎的一种严重且危及生命的并发症。我们描述了一例近期患类风湿关节炎的患者发生闭塞性细支气管炎伴机化性肺炎的病例，该患者表现为严重呼吸功能不全。通过开胸肺活检做出诊断。使用皮质类固醇治疗后呼吸症状迅速缓解且显著改善。同时血清学检测滴度大幅升高，提示闭塞性细支气管炎伴机化性肺炎与类风湿关节炎之间存在关联。
