Roberts D F
Department of Human Genetics, University of Newcastle upon Tyne, England.
Genet Epidemiol. 1991;8(3):147-51. doi: 10.1002/gepi.1370080302.
For all patients with multiple sclerosis in Orkney who were alive in 1974 or who had died during 1958 to 1974, pedigree data were analysed. The relationship between their parents, expressed by kinship coefficients, was compared with that between parents of matched controls. The closer relationship between parents of patients suggests that it is the genes that are shared by a patient's parents, and that he inherits from both, that influence his susceptibility to multiple sclerosis.
对于奥克尼郡所有在1974年尚在世或在1958年至1974年间死亡的多发性硬化症患者，对其家系数据进行了分析。通过亲属系数表示的患者父母之间的关系，与匹配对照组父母之间的关系进行了比较。患者父母之间更紧密的关系表明，正是患者父母共有的、且患者从双方继承的基因，影响了他对多发性硬化症的易感性。
