Amer M, Tosson Z, Soliman A, Selim A G, Salem A, al-Gendy A A
Department of Dermatology and Venereology, Zagazig University, Faculty of Medicine, Egypt.
Int J Dermatol. 1991 Oct;30(10):738-40. doi: 10.1111/j.1365-4362.1991.tb02624.x.
To assess the role of levamisole in treatment of different types of warts, a double-blind study was conducted on 40 patients with different types of warts. Patients were divided into two equal groups, A and B. Group A received levamisole 5 mg/kg body weight on 3 consecutive days every 2 weeks for a period up to 5 months, while patients of group B received placebo for the same period. In group A, 12 patients showed complete cure (60%), two showed partial cure (10%), and the remaining six patients showed no response (30%). In group B, complete cure was achieved only in one case. The higher cure rate was observed in plane and common warts, while plantar warts showed no improvement with levamisole treatment.
为评估左旋咪唑在治疗不同类型疣中的作用,对40例不同类型疣患者进行了一项双盲研究。患者被分为A、B两组,每组人数相等。A组每2周连续3天接受5mg/kg体重的左旋咪唑治疗,疗程长达5个月,而B组患者在同一时期接受安慰剂治疗。A组中,12例患者完全治愈(60%),2例部分治愈(10%),其余6例患者无反应(30%)。B组仅1例完全治愈。扁平疣和寻常疣的治愈率较高,而跖疣接受左旋咪唑治疗后无改善。