Yadav Naveen Kr, Almoqbel Fahad, Head Liseann, Irving Elizabeth L, Leat Susan J
University of Waterloo, Waterloo, ON, Canada.
Doc Ophthalmol. 2009 Oct;119(2):109-21. doi: 10.1007/s10633-009-9177-6. Epub 2009 Jun 24.
In order to develop criteria for the range of data points used for regression line fitting in sweep visually evoked potential (sVEP), which would be objective, clearly specified and give good repeatability and validity, and in order to investigate the effect of luminance on sVEP measurement, visual acuity (VA) and contrast sensitivity (CS) were measured with sVEP in adults aged 17-30 years and children aged 6-8 years. Six to ten participants took part in each experiment. Five criteria (C0-C4) for fitting the regression line were implemented. Test-retest repeatability and validity against psychophysical thresholds at three luminance levels were considered for thresholds and the number of acceptable readings. There were significant effects of criteria (repeated measures ANOVAs, P < 0.05). The criteria, C2 and C3 (based on the range over which the signal-to-noise ratio >or=1), consistently gave better VA and CS, more viable readings, better agreement with psychophysical thresholds in adults and better repeatability than the other criteria. In the case of adults, C2 gave thresholds that were not significantly different from the psychophysical thresholds (P > 0.05). There was little effect of luminance over the 25-100 cd/m(2) range used. Overall, C2 performed the best and would be the criterion of choice, giving better repeatability, better validity and more viable plots.
为了制定用于扫描视觉诱发电位（sVEP）中回归线拟合的数据点范围的标准，该标准应客观、明确规定，并具有良好的可重复性和有效性，同时为了研究亮度对sVEP测量的影响，对17 - 30岁的成年人和6 - 8岁的儿童进行了sVEP测量视觉敏锐度（VA）和对比敏感度（CS）。每个实验有6至10名参与者。实施了五个用于拟合回归线的标准（C0 - C4）。针对阈值和可接受读数的数量，考虑了在三个亮度水平下相对于心理物理学阈值的重测可重复性和有效性。标准有显著影响（重复测量方差分析，P < 0.05）。标准C2和C3（基于信噪比≥1的范围）始终比其他标准给出更好的VA和CS、更多可行的读数、与成年人心理物理学阈值更好的一致性以及更好的可重复性。对于成年人，C2给出的阈值与心理物理学阈值无显著差异（P > 0.05）。在所使用的25 - 100 cd/m²范围内，亮度影响很小。总体而言，C2表现最佳，将是首选标准，具有更好的可重复性、更好的有效性和更可行的图表。
