Stone J, Mukherjee T M, Hecker R
Arch Pathol Lab Med. 1977 Aug;101(8):437-41.
Small spherical, extracellular bodies (C bodies) measuring 20 to 80 nm in diameter and enclosed by a trilaminar membrane 7 nm wide surrounded the microvilli of human rectal epithelial cells. Similar bodies were observed within membrane-bound vesicles (R bodies) in the apical cytoplasm. The C bodies associated with the mature epithelial cells of the luminal surface were more numerous than those associated with the immature cells of the crypts, where the R bodies predominated. A decreased number of C bodies was observed in ulcerative colitis. We concluded that the membrane-bound C bodies surrounding the microvilli were cellular in origin and arose from R bodies within the cytoplasm of the rectal epithelial cells.
直径为20至80纳米的小的球形细胞外小体（C小体），被一层7纳米宽的三层膜所包围，围绕着人类直肠上皮细胞的微绒毛。在顶端细胞质中膜结合囊泡（R小体）内观察到类似的小体。与腔表面成熟上皮细胞相关的C小体比与隐窝未成熟细胞相关的C小体更多，在隐窝处R小体占主导。在溃疡性结肠炎中观察到C小体数量减少。我们得出结论，围绕微绒毛的膜结合C小体起源于细胞，源自直肠上皮细胞质内的R小体。
