Diestelhorst M, Krieglstein G K
Department of Ophthalmology, University of Cologne, Köln, Germany.
J Fr Ophtalmol. 1991;14(4):255-9.
The influence of posterior chamber lens implantation on the aqueous humor dynamics was investigated using anterior chamber fluorophotometry before and 9 weeks after cataract extraction and IOL implantation. 34 Patients finished the protocol. Patients with preexisting glaucoma or those having a history of ocular or systemic inflammation were excluded from the study, also those taking topical or systemic drugs with potential influence on the aqueous humor dynamics. 9 weeks after IOL implantation, a mean increase in aqueous humor flow was notified. This increase was highly significant (p less than 0.01, Students paired t-test). There were no significant changes in aqueous humor dynamics in the unoperated, fellow eyes which served as controls. The significant difference of aqueous humor flow 9 weeks after cataract extraction and IOL implantation indicates that the liberation of prostaglandins may cause an increase of outflow facility as well as pseudo-facility.
利用前房荧光光度测定法，在白内障摘除及人工晶状体植入术前和术后9周，研究后房型人工晶状体植入对房水动力学的影响。34例患者完成了该方案。患有青光眼或有眼部或全身炎症病史的患者被排除在研究之外，服用对房水动力学有潜在影响的局部或全身药物的患者也被排除。人工晶状体植入术后9周，房水流量平均增加。这种增加非常显著（p<0.01，学生配对t检验）。作为对照的未手术的对侧眼的房水动力学没有显著变化。白内障摘除及人工晶状体植入术后9周房水流量的显著差异表明，前列腺素的释放可能导致流出易度以及假性易度增加。
