Kondo T, Yamauchi T, Nakatsu A
Department of Ophthalmology, Kobe City General Hospital, Japan.
J Cataract Refract Surg. 1995 Nov;21(6):706-9. doi: 10.1016/s0886-3350(13)80571-8.
We evaluated changes in aqueous outflow and blood-aqueous barrier (BAB) disruption after cataract surgery in two randomly selected groups of eyes. In one group, a high-viscosity viscoelastic was used for intraocular lens (IOL) implantation; in the other, a low-viscosity viscoelastic. Fluorophotometry was used to evaluate aqueous humor dynamics five to seven hours after IOL implantation. Aqueous outflow after IOL implantation in operated eyes was nearly twice that in the fellow eyes, which served as controls. Mean protein concentration in the anterior chamber was also elevated in operated eyes. However, postoperative aqueous outflow did not differ significantly between the two groups. The substantial increase in aqueous outflow observed postoperatively and the increase in aqueous humor protein concentration were closely related to BAB disruption. These results suggest that BAB disruption may be a main cause of the transient high intraocular pressure observed after IOL implantation in both groups.
我们评估了随机选择的两组眼睛在白内障手术后房水流出和血-房水屏障（BAB）破坏的变化。一组使用高粘度粘弹剂进行人工晶状体（IOL）植入；另一组使用低粘度粘弹剂。在IOL植入后5至7小时，使用荧光光度法评估房水动力学。手术眼IOL植入后的房水流出量几乎是作为对照的对侧眼的两倍。手术眼的前房平均蛋白质浓度也升高。然而，两组术后房水流出量没有显著差异。术后观察到的房水流出量的大幅增加以及房水蛋白质浓度的增加与BAB破坏密切相关。这些结果表明，BAB破坏可能是两组IOL植入后观察到的短暂高眼压的主要原因。
