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[颈椎疾病患者所获骨组织不脱钙切片的组织形态计量学研究]

[A hist-morphometrical study of undecalcified sections of bone obtained in patients with cervical disorders].

作者信息

Wakisaka A

机构信息

Department of Orthopedic Surgery, Yamaguchi University, School of Medicine, Japan.

出版信息

Nihon Seikeigeka Gakkai Zasshi. 1991 Aug;65(8):536-49.

PMID:1955799
Abstract

Histomorphometrical parameters were used to investigate bone metabolism in patients with symptomatic cervical disorders, especially those patients with ossification of the posterior longitudinal ligament (OPLL) of the cervical spine. There were 19 patients in this study. The patients were divided into two groups depending on the presence of OPLL. Six patients had OPLL (OPLL group), 13 patients did not (non-OPLL group). All patients received pre-operative labelling with tetracycline. There was a positive correlation between vertebral body and iliac bone in the parameters of trabecular osteoid specific volume, relative osteoid volume and relative formation surface. The vertebra/ilium ratio of the mineral apposition rate, which suggests bone formation in vertebral body relatively, was higher in OPLL group significantly. The present study concludes that OPLL can be considered a condition of hyperostosis though, bone formation ability in the vertebral body of OPLL is higher than in the ilium.

摘要

组织形态计量学参数用于研究有症状的颈椎疾病患者的骨代谢,尤其是那些患有颈椎后纵韧带骨化(OPLL)的患者。本研究中有19名患者。根据是否存在OPLL将患者分为两组。6名患者有OPLL(OPLL组),13名患者没有(非OPLL组)。所有患者术前均用四环素进行标记。在小梁类骨质比容、相对类骨质体积和相对形成表面等参数方面,椎体与髂骨之间存在正相关。提示椎体相对骨形成的矿化沉积率的椎骨/髂骨比值在OPLL组显著更高。本研究得出结论,虽然OPLL可被视为一种骨质增生的情况,但OPLL椎体的骨形成能力高于髂骨。

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