Yin Wei-min, Gao Jian-hua, Yang Qing-fang, Lu Feng, Ye Jia-jia
Department of Plastic Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510000, China.
Zhonghua Zheng Xing Wai Ke Za Zhi. 2009 Mar;25(2):140-3.
To study the feasibility of Polyvinylpolypyrrolidone (PVPP)/silicone composite automatic expanded material as implants.
The PVPP hydrogel was mixed with silicone through the location at the high temperature. Implants with different ratio of PVPP to silicone were placed under the back and nose skin in 24 New Zealand rabbits. The surrounding tissue reaction, material and skin expansion were observed and compared with those with pure silicone implants.
The study lasted for 200 days. Compared with pure silicone implants, the composite material could expand automatically and stop expanding at about 2 weeks after implantation. Histological study showed similar inflectional and foreign body reaction around the composite material and the pure silicone.
Compared with pure silicone, the PVPP/silicone composite implant has the advantage of automatic expansion, so as to expand the soft tissue.
研究聚乙烯聚吡咯烷酮（PVPP）/硅胶复合自动扩张材料作为植入物的可行性。
通过高温定位将PVPP水凝胶与硅胶混合。将不同PVPP与硅胶比例的植入物置于24只新西兰兔的背部和鼻部皮肤下。观察周围组织反应、材料及皮肤扩张情况，并与纯硅胶植入物进行比较。
研究持续200天。与纯硅胶植入物相比，复合材料可自动扩张，并在植入后约2周停止扩张。组织学研究显示复合材料和纯硅胶周围的炎症和异物反应相似。
与纯硅胶相比，PVPP/硅胶复合植入物具有自动扩张的优势，从而可扩张软组织。
