Departments of Neurology, School of Medicine, State University of Campinas (UNICAMP), Campinas, Brazil.
J Neuroimaging. 2010 Oct;20(4):397-9. doi: 10.1111/j.1552-6569.2009.00393.x.
Sensory neuronopathies (SN) are peripheral nervous system disorders associated with degeneration of dorsal root ganglion neurons. Magnetic resonance imaging (MRI) studies have shown abnormalities limited to T2-weighted high signal intensity in the posterior columns.
A 65-year-old woman with Sjögren syndrome had slowly progressive unsteadiness of gait and limb paresthesias. A blink reflex examination suggested a paramedian brainstem lesion, confirmed by MRI.
Sjögren's syndrome-related SN may be associated with a more diffuse immune-mediated aggression, involving also the brainstem, and leading to some of the blink reflex abnormalities observed in nonparaneoplastic SN.
感觉神经元病（SN）是一种与背根神经节神经元变性相关的周围神经系统疾病。磁共振成像（MRI）研究显示，异常仅限于后柱的 T2 加权高信号强度。
一名 65 岁的干燥综合征女性患者出现步态不稳和四肢感觉异常进行性加重。眨眼反射检查提示中脑旁病变，MRI 证实了这一点。
干燥综合征相关的 SN 可能与更广泛的免疫介导的攻击有关，也涉及脑干，并导致一些在非副肿瘤性 SN 中观察到的眨眼反射异常。
