[初级听觉皮层的功能磁共振研究结果（I）：一般特征和个体结果]
[Results of a functional magnetic resonance study of the primary auditory cortex (I): general characteristics and individual outcomes].
作者信息
Menéndez-Colino Luis M, Traserra Josep, Falcón Carles, Berenguer Joan, Pujol Teresa, Doménech Joan, Bernal-Sprekelsen Manuel
机构信息
Servicio de Otorrinolaringología, Hospital Virgen de la Salud, Toledo, España.
出版信息
Acta Otorrinolaringol Esp. 2009 May-Jun;60(3):160-8.
OBJECTIVE
To demonstrate and investigate the activation patterns of the primary auditory cortex (Heschl's gyrus) using functional magnetic resonance imaging (fMRI).
MATERIAL AND METHODS
Pure tone stimuli at 750 Hz and 2000 Hz were delivered to the right and left ear of 32 normal-hearing volunteers (18-49 years old) in 20-second on-off cycles. The fMRI data were obtained using a 1.5 Tesla scanner and processed with SPM2.
RESULTS
For both tone frequencies, bilateral hemispheric activation was identified in the transverse temporal gyrus (Heschl's gyrus) in 29 subjects (90.62 %) in response to pure tone stimuli with a probability level of p < 0.001. For monaural stimulation, bilateral hemispheric activation was observed with generally greater extent of activation in the Heschl's gyrus (HG) contralateral to the stimulated ear.
CONCLUSIONS
These results demonstrate that fMRI is a useful imaging technique to investigate the auditory cortex. The contralateral auditory cortex is more responsive than the ipsilateral cortex to tones presented monaurally.
目的
使用功能磁共振成像（fMRI）来展示和研究初级听觉皮层（颞横回）的激活模式。
材料与方法
以20秒开-关周期，将750赫兹和2000赫兹的纯音刺激分别施加于32名听力正常的志愿者（年龄18 - 49岁）的右耳和左耳。使用1.5特斯拉扫描仪获取fMRI数据，并采用SPM2进行处理。
结果
对于两种音调频率，在29名受试者（90.62%）中，响应纯音刺激时，双侧半球在颞横回（颞横回）均有激活，概率水平为p < 0.001。对于单耳刺激，观察到双侧半球激活，通常在受刺激耳对侧的颞横回（HG）中激活程度更大。
结论
这些结果表明，fMRI是一种用于研究听觉皮层的有用成像技术。对单耳呈现的音调，对侧听觉皮层比同侧皮层反应更灵敏。
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