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甲状腺功能异常性眼眶病的外科治疗

Surgical treatment of dysthyroid orbitopathy.

作者信息

Chu Eugene A, Miller Neil R, Grant Michael P, Merbs Shannath, Tufano Ralph P, Lane Andrew P

机构信息

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Hospital, Baltimore, MD 21287-0910, USA.

出版信息

Otolaryngol Head Neck Surg. 2009 Jul;141(1):39-45. doi: 10.1016/j.otohns.2009.04.004.

Abstract

OBJECTIVES

Orbital decompression for dysthyroid orbitopathy may be performed by open or transnasal endoscopic approaches; however, criteria for the selection of the appropriate surgical technique have not been well-defined. Our goal was to compare the surgical outcomes of orbital decompression techniques employed by the otolaryngology and ophthalmology services at a single institution, so as to clarify the indications and develop a rationale for optimal management.

STUDY DESIGN

Case series with chart review.

SETTING

Tertiary care academic medical center.

SUBJECTS AND METHODS

Orbital decompressions on 112 orbits of 69 patients from 2001 to 2008 at a tertiary care academic medical center.

RESULTS

The majority (83%) of orbital decompressions were performed primarily for proptosis, whereas the remainder was indicated for dysthyroid optic neuropathy. Maximum reduction of proptosis was achieved with an endoscopic medial and inferior orbital wall decompression combined with a lateral orbitotomy with fat removal. The average reduction in proptosis was 7.4 mm+/-2.3 mm (primary surgery for proptosis). The endoscopic approach alone provided the least average proptosis reduction but was highly successful in the treatment of dysthyroid optic neuropathy.

CONCLUSIONS

A three-wall decompression using a combined endoscopic and external approach provides the greatest amount of decompression. The endoscopic approach as a single modality is best suited for patients with mild proptosis and for patients with dysthyroid optic neuropathy. Cooperation between otolaryngology and ophthalmology achieves the best care for patients with thyroid eye disease who require surgical treatment.

摘要

目的

甲状腺相关眼病的眼眶减压术可通过开放手术或经鼻内镜手术进行;然而,选择合适手术技术的标准尚未明确界定。我们的目标是比较同一机构耳鼻喉科和眼科所采用的眼眶减压技术的手术效果,以明确适应症并制定优化治疗的理论依据。

研究设计

病例系列研究并进行病历回顾。

研究地点

三级医疗学术医学中心。

研究对象与方法

2001年至2008年期间,在一家三级医疗学术医学中心对69例患者的112只眼眶进行眼眶减压术。

结果

大多数(83%)眼眶减压术主要用于治疗眼球突出,其余则用于治疗甲状腺相关视神经病变。内镜下内侧和下壁眼眶减压联合外侧眶切开术并去除脂肪可实现最大程度的眼球突出减轻。眼球突出的平均减轻量为7.4毫米±2.3毫米(针对眼球突出的初次手术)。单纯内镜手术导致的眼球突出平均减轻量最少,但在治疗甲状腺相关视神经病变方面非常成功。

结论

采用内镜和外部联合方法进行三壁减压可提供最大程度的减压。单纯内镜手术最适合轻度眼球突出患者以及患有甲状腺相关视神经病变的患者。耳鼻喉科和眼科之间的合作可为需要手术治疗的甲状腺眼病患者提供最佳治疗。

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