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越南一项关于 Graves 眼眶病的内镜下眼眶减压术研究。

Endoscopic Orbital Decompression for Graves' Orbitopathy - A Vietnam Study.

作者信息

Pham Thi My Hanh, Nguyen Chien Thang, Mai Quoc Tung, Bui Thi Huong Giang, Do Dung Hoa, McCluskey Peter, Pham Trong Van

机构信息

Department of Ophthalmology, 103 Military Hospital, Hanoi, Vietnam.

Department of Ophthalmology, Hanoi Medical University, Hanoi, Vietnam.

出版信息

Clin Ophthalmol. 2021 Apr 22;15:1685-1690. doi: 10.2147/OPTH.S290784. eCollection 2021.

Abstract

PURPOSE

To evaluate the efficacy and safety of endoscopic orbital decompression in patients with Graves' orbitopathy.

PATIENTS AND METHODS

This is a prospective study in Hanoi Medical University and a Military Hospital from December 2017 to December 2018. Twenty-eight orbits of fifteen patients were undergoing endoscopic orbital decompression for Graves' orbitopathy. Indications for surgery were proptosis in twenty-two orbits and compressive optic neuropathy in six orbits. The outcome measures were proptosis reduction, visual acuity, visual field test and diplopia. Post-operative complications including cerebrospinal fluid leakage, haemorrhage, lacrimal duct impairment, worsening diplopia, sinusitis and cellulitis were collected.

RESULTS

The mean proptosis reduction was 2.23 mm. Visual acuity and medium deviation in the Humphrey visual field were significantly improved in four of six eyes with compressive optic neuropathy. There was one patient with intra-operative excessive bleeding which resolved without affecting visual outcome. Post-operatively, two patients developed a new onset of diplopia and two others worsened diplopia; three have already undergone successful strabismus surgery and moderate proptosis reduction.

CONCLUSION

Endoscopic orbital decompression surgery was effectively and safely to manage compressive optic neuropathy of Graves' orbitopathy and moderately reduce proptosis in a group of Vietnamese patients.

摘要

目的

评估内镜下眼眶减压术治疗格雷夫斯眼眶病患者的疗效和安全性。

患者与方法

这是一项于2017年12月至2018年12月在河内医科大学和一家军事医院开展的前瞻性研究。15例患者的28只眼眶接受了内镜下眼眶减压术治疗格雷夫斯眼眶病。手术指征为22只眼眶存在眼球突出,6只眼眶存在压迫性视神经病变。观察指标为眼球突出度降低、视力、视野检查和复视情况。收集术后并发症,包括脑脊液漏、出血、泪道损伤、复视加重、鼻窦炎和蜂窝织炎。

结果

平均眼球突出度降低2.23毫米。6只存在压迫性视神经病变的眼睛中,有4只的视力和汉弗莱视野中的平均偏差有显著改善。有1例患者术中出血过多,但未影响视力结果,出血自行缓解。术后,2例患者出现新发复视,另外2例患者复视加重;3例患者已成功接受斜视手术,眼球突出度适度降低。

结论

内镜下眼眶减压术在一组越南患者中能有效且安全地治疗格雷夫斯眼眶病的压迫性视神经病变,并适度降低眼球突出度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9ec5/8075304/01f1f4ac9746/OPTH-15-1685-g0001.jpg

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