Culp Brittney, Scheinfeld Noah
Ms. Culp is a fourth-year medical student at Texas Tech University School of Medicine in Amarillo, Texas. Dr. Scheinfeld is Assistant Professor at Columbia University and a dermatologist in private practice. He can be reached at 30 Central Park South, Suite 2D, New York, NY 10019 (212-991-6490).
P T. 2009 Jan;34(1):38-45.
Rosacea is a chronic inflammatory condition of the facial skin affecting the blood vessels and pilosebaceous units. Rosacea is more common in persons of northern and western European descent with a fair complexion, but it can affect skin of any color. Although symptoms may wax and wane during the short term, rosacea can progress with time. Patients usually present with complaints of flushing and blushing and sensitive skin, and their skin may be especially irritated by topical preparations. Rosacea has a variety of triggers; however, they may be unnoticed by the patient.Standard treatments approved by the FDA include azelaic acid, topical metronidazole, and oral tetracyclines, in particular minocycline and doxycycline. Other topical treatments include topical clindamycin, subantimicrobial-dose doxycycline, and sulfur products. Azithromycin and controlled-release minocycline are possible options for treating rosacea, but the FDA has not approved either agent for this indication.
酒渣鼻是一种影响面部皮肤血管和皮脂腺单位的慢性炎症性疾病。酒渣鼻在北欧和西欧血统、肤色白皙的人群中更为常见，但它可影响任何肤色的皮肤。尽管症状在短期内可能会有起伏，但酒渣鼻会随着时间推移而发展。患者通常表现为面部潮红、皮肤敏感，其皮肤可能对局部用药特别敏感。酒渣鼻有多种诱发因素；然而，患者可能并未注意到这些因素。美国食品药品监督管理局（FDA）批准的标准治疗方法包括壬二酸、外用甲硝唑和口服四环素，尤其是米诺环素和多西环素。其他局部治疗方法包括外用克林霉素、亚抗菌剂量的多西环素和硫磺产品。阿奇霉素和控释米诺环素可能是治疗酒渣鼻的选择，但FDA尚未批准这两种药物用于此适应症。
