两岁和三岁纯种马的骨生物标志物与骨折风险
Bone biomarkers and risk of fracture in two- and three-year-old Thoroughbreds.
作者信息
Jackson B F, Dyson P K, Lonnell C, Verheyen K L P, Pfeiffer D U, Price J S
机构信息
Department of Veterinary Clinical Sciences, Hawkshead Lane, Hatfield, Hertfordshire AL9 7TA, UK.
出版信息
Equine Vet J. 2009 Apr;41(4):410-3. doi: 10.2746/042516409x416206.
The aim of this study was to determine whether bone biomarkers (osteocalcin, PICP, ICTP and CTX-I) could be used to identify 2- and 3-year-olds at increased risk of fracture in the subsequent flat racing season. It was concluded that these bone biomarkers cannot be used to identify 2- and 3-year-olds that sustain a fracture. Whether bone biomarkers have better predictive value in older horses or when measured serially in the same animal remains to be determined.
本研究的目的是确定骨生物标志物（骨钙素、I型前胶原羧基端前肽、I型胶原羧基端交联肽和I型胶原交联C端肽）是否可用于识别在随后的平地赛马赛季中骨折风险增加的2岁和3岁马匹。研究得出结论，这些骨生物标志物不能用于识别发生骨折的2岁和3岁马匹。骨生物标志物在年龄较大的马匹中是否具有更好的预测价值，或者在同一动物中进行连续测量时是否具有更好的预测价值，仍有待确定。
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