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生物精神病学中的磁共振成像

Magnetic resonance imaging in biological psychiatry.

作者信息

Na C, Doraiswamy P M, Lee K H, Krishnan K R

机构信息

Department of Psychiatry, Duke University Medical Center, Durham, North Carolina.

出版信息

Prog Neuropsychopharmacol Biol Psychiatry. 1991;15(5):581-93. doi: 10.1016/0278-5846(91)90048-6.

DOI:10.1016/0278-5846(91)90048-6
PMID:1956987
Abstract
  1. Although clinicians have been quick to adopt magnetic resonance imaging (MRI) in the search for brain pathology in psychiatric disorders, the clinical utility of MRI is only now being well defined. 2. Numerous past computerized tomography or post-mortem tissue reports in patients with schizophrenia, affective disorders, dementia, autism, and many other psychiatric illnesses have suggested neuroanatomical substrates for these disorders. However, these techniques have several limitations. 3. The advent of MRI has allowed a high resolution method for examining the brain in vivo. It is important for psychiatrists to know the clinical utility, and the advantages/disadvantages of MR compared with CT. 4. In this article, the authors review the relevant MR literature with some illustrative cases where MRI provided clinically useful information. Recent advances in MRI technology that will have future applications in psychiatry are also discussed.
摘要
  1. 尽管临床医生已迅速采用磁共振成像(MRI)来查找精神疾病中的脑部病变,但MRI的临床效用目前才得到明确界定。2. 过去,针对精神分裂症、情感障碍、痴呆、自闭症及许多其他精神疾病患者的大量计算机断层扫描或尸检组织报告已提示这些疾病存在神经解剖学基础。然而,这些技术存在若干局限性。3. MRI的出现使得在活体状态下检查大脑有了一种高分辨率方法。精神科医生了解MRI的临床效用以及与CT相比的优缺点很重要。4. 在本文中,作者回顾了相关的MRI文献,并列举了一些MRI提供了临床有用信息的病例。还讨论了MRI技术在精神病学领域未来会有应用的最新进展。

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引用本文的文献

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2
Neuroimaging and genetics of borderline personality disorder: a review.边缘型人格障碍的神经影像学与遗传学:综述
J Psychiatry Neurosci. 2007 May;32(3):162-73.
3
Some methodological issues in neuroradiological research in psychiatry.精神病学神经放射学研究中的一些方法学问题。
J Neural Transm Gen Sect. 1995;99(1-3):7-54. doi: 10.1007/BF01271468.
4
The relations between neuroscience and human behavioral science.神经科学与人类行为科学之间的关系。
J Exp Anal Behav. 1994 Mar;61(2):307-17. doi: 10.1901/jeab.1994.61-307.