Micheau C
Cancer. 1977 Jul;40(1):314-8. doi: 10.1002/1097-0142(197707)40:1<314::aid-cncr2820400144>3.0.co;2-7.
A close collaboration between E.N.T. surgeons and pathologists permitted us to obtain 6 cases of olfactory esthesioneuroma in which fresh tumor tissue was available. Histochemical and biochemical studies were made in comparison with neuroblastoma. Different reactions and assays performed revealed a similarity with sympathetic tumors. Moreover, the presence of catecholamines in esthesioneuroma provides a great help in diagnostic as does electron microscope examination.
耳鼻喉科外科医生与病理学家的密切合作使我们获得了6例可获取新鲜肿瘤组织的嗅神经母细胞瘤病例。我们进行了组织化学和生化研究,并与神经母细胞瘤进行了比较。所进行的不同反应和检测显示出与交感神经肿瘤的相似性。此外,嗅神经母细胞瘤中儿茶酚胺的存在以及电子显微镜检查对诊断有很大帮助。