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间变性大细胞淋巴瘤:世界卫生组织分类的变化及靶向治疗前景

Anaplastic large cell lymphoma: changes in the World Health Organization classification and perspectives for targeted therapy.

作者信息

Falini Brunangelo, Martelli Maria Paola

出版信息

Haematologica. 2009 Jul;94(7):897-900. doi: 10.3324/haematol.2009.008250.

Abstract

The accompanying perspective by Drs. Falini and Martelli provides a clear description of the current WHO classification with a focus on the distinction between ALK-positive anaplastic large cell lymphoma ALCL and ALK-negative disease. Additionally, they provide a rationale for potential new targets for therapy including flavopiridol. See related paper on page 944.

摘要

法利尼博士和马尔泰利博士随附的观点明确描述了世界卫生组织的现行分类,重点在于ALK阳性间变性大细胞淋巴瘤(ALCL)与ALK阴性疾病之间的区别。此外,他们还阐述了包括黄酮哌啶醇在内的潜在新治疗靶点的理论依据。见第944页的相关论文。

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