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[双侧光滑念珠菌肺炎]

[Bilateral Torulopsis glabrata pneumonia].

作者信息

Gueteau N, Darras A, Croxo C, Mulliez P

机构信息

Service de Pneumologie, Hôpital Saint Philibert, Lomme.

出版信息

Rev Pneumol Clin. 1991;47(3):137-9.

PMID:1957105
Abstract

In a 48-year old male patient hospitalized for evaluation of fatigue with non-productive cough and dyspnoea, standard radiography and computerized tomography of the chest showed nodular opacities in both lung apices. Examination of intrabronchial specimens revealed mycelial filaments, and Torulopsis glabrata grew in culture. Under antifungal treatment the clinical signs rapidly improved and the radiological abnormalities disappeared more slowly, which confirmed the diagnosis of T. glabrata pneumonia. The authors recall the pathogenic role of this yeast-like fungus, closely related to Candida albicans, which mainly causes severe opportunistic infections. The diagnostic criteria, the part played by immunodepression in the disease and the therapeutic problems encountered are also discussed.

摘要

一名48岁男性患者因疲劳、干咳和呼吸困难入院接受评估,胸部标准X线摄影和计算机断层扫描显示双肺尖有结节状阴影。支气管内标本检查发现菌丝,培养出光滑念珠菌。在抗真菌治疗下,临床症状迅速改善,而放射学异常消失得较慢,这证实了光滑念珠菌肺炎的诊断。作者回顾了这种与白色念珠菌密切相关的酵母样真菌的致病作用,它主要引起严重的机会性感染。还讨论了诊断标准、免疫抑制在该病中的作用以及遇到的治疗问题。

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