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小儿择期声门上气道装置的评论

A critique of elective pediatric supraglottic airway devices.

作者信息

White Michelle C, Cook Tim M, Stoddart Peter A

机构信息

Department of Paediatric Anaesthesia, Bristol Royal Hospital for Children, Marlborough Street, Bristol, UK.

出版信息

Paediatr Anaesth. 2009 Jul;19 Suppl 1:55-65. doi: 10.1111/j.1460-9592.2009.02997.x.

Abstract

In 1988, when the Laryngeal Mask Airway-Classic (Intavent Orthofix, Maidenhead, UK), was introduced there were only two choices of airway management: tracheal tube or facemask. The supraglottic airway, as we now understand the term, did not exist. Yet, 20 years later, we are faced with an ever increasing choice of supraglottic airway devices (SAD). For many SADs, with the exception of the LMA-Classic and LMA-Proseal (Intavent Orthofix, Maidenhead, UK), there is a lack of high quality data of efficacy. The best evidence requires a randomized controlled trial comparing a new device against an established alternative, properly powered to detect clinically relevant differences in clinically important outcomes. Such studies in children are very rare. Safety data is even harder to establish particularly for rare events such as aspiration. Therefore, most safety data comes from extended use rather than high quality evidence which inevitably biases against newer devices. For reason of these factors, claims of efficacy and particularly safety must be interpreted cautiously. This narrative review aims to present the evidence surrounding the use of currently available pediatric SADs in routine anesthetic practice.

摘要

1988年,当经典喉罩气道(英国梅登黑德的Intavent Orthofix公司生产)问世时,气道管理仅有两种选择:气管导管或面罩。我们现在所理解的声门上气道当时并不存在。然而,20年后,我们面临着越来越多的声门上气道装置(SAD)可供选择。对于许多SAD而言,除了经典喉罩气道和双管喉罩气道(英国梅登黑德的Intavent Orthofix公司生产)外,缺乏关于其疗效的高质量数据。最佳证据需要进行一项随机对照试验,将一种新装置与一种既定的替代装置进行比较,样本量要足够大,以便能够检测出在临床重要结局方面具有临床相关性的差异。此类针对儿童的研究非常罕见。安全数据更难确定,尤其是对于诸如误吸等罕见事件。因此,大多数安全数据来自于广泛使用,而非高质量证据,这不可避免地对新型装置不利。由于这些因素,对于疗效尤其是安全性的宣称必须谨慎解读。本叙述性综述旨在呈现关于在常规麻醉实践中使用现有儿科SAD的相关证据。

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