Hortsch M, Bieber A J
Department of Anatomy and Cell Biology, University of Michigan, Ann Arbor 48109-0616.
Trends Biochem Sci. 1991 Aug;16(8):283-7. doi: 10.1016/0968-0004(91)90116-d.
The assignment of specific roles to cell-surface proteins by standard methods can be a major problem. In the technique described below, Schneider-2 (S2) cells, an established Drosophila cell line, have been used in cell transfection and aggregation experiments. As such, they have proved to be a useful tool for the functional characterization of putative cell-adhesion molecules.
