Møller A L, Larsen U T, Andersen J B, Olesen A S
Anaestesiafdelingen og abdominalkirurgisk afedling, Aalborg Sygehus Syd.
Ugeskr Laeger. 1991 Nov 25;153(48):3408-10.
A material of 100 patients aged 18-70 years, ASA groups 1-2, who were otherwise healthy with slight generalized sequelae of their illness but without limitations in their usual habits, who were admitted for gastroscopy were randomized to sedation with either diazepam or propofol. Prior to the examination, 0.2 mg/kg diazepam or 1 mg/kg propofol was administered. If necessary, this was supplemented with half of the initial dosage. No difference were found in the sedation. Patients in the propofol group remembered the surgeon's information significantly better and woke significantly more rapidly. Propofol caused significantly more pain on injection. We consider that propofol can be employed for outpatient gastroscopy.
选取100例年龄在18至70岁之间、ASA分级为1至2级的患者，这些患者身体健康，虽有轻微全身性疾病后遗症，但日常活动无限制，因接受胃镜检查入院，将其随机分为地西泮镇静组或丙泊酚镇静组。检查前，给予0.2mg/kg地西泮或1mg/kg丙泊酚。如有必要，补充初始剂量的一半。两组镇静效果无差异。丙泊酚组患者对医生信息的记忆明显更好，苏醒也明显更快。丙泊酚注射时疼痛明显更剧烈。我们认为丙泊酚可用于门诊胃镜检查。
