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[一例胰腺孤立性纤维瘤]

[A case of solitary fibrous tumor of the pancreas].

作者信息

Ishiwatari Hirotoshi, Hayashi Tsuyoshi, Yoshida Makoto, Kuroiwa Ganji, Sato Yasushi, Kobune Masayoshi, Takimoto Rishu, Kimura Yasutoshi, Hasegawa Tadashi, Hirata Koichi, Kato Junji

机构信息

4th Department of Internal Medicine, Sapporo Medical University.

出版信息

Nihon Shokakibyo Gakkai Zasshi. 2009 Jul;106(7):1078-85.

Abstract

A 58-year-old woman without any clinical symptoms had a routine health check-up, during which a mass in the head of the pancreas was detected by US. Abdominal US showed a round, hypoechogenic nodule of the pancreatic head. The tumor measured 3cm in diameter and contained an anechoic area. CT revealed a well-demarcated tumor in the pancreatic head. The tumor was partially enhanced by contrast medium, but the left portion of the tumor, which US had shown to be an anechoic area was not enhanced. Imaging findings suggested an endocrine tumor with cystic changes. A pylorus-preserving pancreatoduodenectomy was performed. The tumor was composed of spindle-shaped cells. There was a typical patternless growth of short fascicles and a short storiform arrangement of cells in the stroma with varying degrees of collagenization. Immunohistochemically, the tumor cells were positive for CD34 and Bcl-2. Based on the light microscopic morphology and immunostaining profile, the tumor was classified as a solitary fibrous tumor (SFT) of the pancreas.

摘要

一名58岁无任何临床症状的女性进行了常规健康检查,期间超声检查发现胰头有一肿块。腹部超声显示胰头有一个圆形低回声结节。肿瘤直径为3cm,内有一无回声区。CT显示胰头有一个边界清晰的肿瘤。肿瘤部分被造影剂增强,但超声显示为无回声区的肿瘤左侧部分未增强。影像学表现提示为伴有囊性变的内分泌肿瘤。行保留幽门的胰十二指肠切除术。肿瘤由梭形细胞组成。在不同程度胶原化的间质中,有短束状典型的无模式生长和细胞的短漩涡状排列。免疫组化显示肿瘤细胞CD34和Bcl-2呈阳性。根据光镜形态和免疫染色特征,该肿瘤被分类为胰腺孤立性纤维瘤(SFT)。

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