Giuliante Felice, Ardito Francesco, Sarno Gerardo, Vellone Maria, Giovannini Ivo, Nuzzo Gennaro
Hepato-Biliary Surgery Unit, Dept. of Surgery, Catholic University of the Sacred Heart School of Medicine, Rome, Italy.
Hepatogastroenterology. 2009 Mar-Apr;56(90):512-4.
Renal cell carcinoma is an aggressive tumor which is often advanced at the time of diagnosis; its distant spread can take a lymphatic route or, more often, a vascular route (renal vein and inferior vena cava), but tumor thrombosis of left portal vein extending into the round ligament (the umbilical vein) coming from this tumor, to our knowledge, has never been described. We report the case of a metastatic thrombosis of left portal vein and of the umbilical vein from renal cell carcinoma, developed 13 years after nephrectomy, which was successfully treated with left hepatectomy. The experience with hepatectomy for metastatic renal cell carcinoma has been rarely reported. Nevertheless radical hepatectomy is considered to be the only opportunity for curative treatment for selected patients with metastatic renal cell carcinoma.
肾细胞癌是一种侵袭性肿瘤,在诊断时往往已处于晚期;其远处转移可通过淋巴途径,或更常见的是通过血管途径(肾静脉和下腔静脉),但据我们所知,来自该肿瘤的左门静脉血栓形成并延伸至圆韧带(脐静脉)的情况从未被描述过。我们报告了一例肾细胞癌导致左门静脉和脐静脉转移性血栓形成的病例,该病例在肾切除术后13年出现,通过左肝切除术成功治疗。关于肝切除术治疗转移性肾细胞癌的经验鲜有报道。然而,根治性肝切除术被认为是某些转移性肾细胞癌患者获得治愈性治疗的唯一机会。