Dinkar Anju, Singh Jitendra
Department of Microbiology, Institute of Medical Science, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Department of Medicine, Narayana Medical College, Sasaram, Bihar, India.
Tzu Chi Med J. 2019 Apr 2;32(1):36-40. doi: 10.4103/tcmj.tcmj_161_18. eCollection 2020 Jan-Mar.
Recently, an alarming rise of dengue has been seen in India which remains a major public health concern. This study has been designed for a comprehensive overview of the epidemiology, gender, age, area distribution, symptomology, and seasonal variability.
Retrospective analysis of 900 suspected dengue cases of all age groups of either sex from 2012 to 2017 at a North Indian tertiary care hospital revealed 461 (51.22%) cases seropositive for dengue.
The age group of 20-30 years was the most affected group with male predominance. The urban population was more affected as 75.05%, and maximum cases were detected in October month followed by November. Common abnormal laboratory parameters were thrombocytopenia (99.1%), hepatic dysfunction (59%), and leukopenia (26.68%). Two uncommon findings, pancytopenia and pancreatic dysfunction were reported in 7 and 3 cases respectively.
Dengue infection in India has evolved rapidly, and regular outbreaks have been observed with a changing epidemiology, as the disease is rapidly spreading from urban to rural areas with increasing atypical manifestations.
最近，印度登革热病例急剧增加，这仍然是一个主要的公共卫生问题。本研究旨在全面概述登革热的流行病学、性别、年龄、地区分布、症状学和季节变化。
对一家印度北部三级护理医院2012年至2017年所有年龄组的900例疑似登革热病例进行回顾性分析，结果显示461例（51.22%）登革热血清学阳性。
20至30岁年龄组受影响最大，男性居多。城市人口受影响更大，占75.05%，10月份检测到的病例最多，其次是11月份。常见的异常实验室参数有血小板减少（99.1%）、肝功能障碍（59%）和白细胞减少（26.68%）。分别有7例和3例报告了全血细胞减少和胰腺功能障碍这两个罕见发现。
印度的登革热感染迅速演变，随着疾病从城市迅速蔓延到农村地区且非典型表现增多，流行病学不断变化，经常出现疫情暴发。
