重度高胆红素血症和核黄疸：新生儿黄疸监测需更加谨慎。

Severe hyperbilirubinaemia and kernicterus: more caution is needed in newborn jaundice surveillance.

作者信息

Allen N M, Mohammad F, Foran A, Corcoran D, Clarke T

机构信息

Department of Paediatrics, Rotunda Hospital, Dublin.

出版信息

Ir Med J. 2009 Jul-Aug;102(7):228-9.

PMID:19772008

Abstract

Since the 1990s, there has been a re-emergence of cases of severe hyperbilirubinaemia and kernicterus. The current UK incidence of bilirubin encephalopathy is 0.9/100,000 with a higher reported incidence in some countries. Three otherwise healthy newborn infants, who presented with severe hyperbilirubinaemia, including one who developed kernicterus, are reported here. Some of the current challenges in newborn jaundice surveillance are highlighted.

摘要

自20世纪90年代以来，严重高胆红素血症和核黄疸病例再度出现。目前英国胆红素脑病的发病率为0.9/10万，在一些国家报告的发病率更高。本文报告了三名原本健康的新生儿，他们出现了严重高胆红素血症，其中一名发展为核黄疸。文中强调了新生儿黄疸监测当前面临的一些挑战。