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耐热分枝杆菌:欧洲罕见分离出的分枝杆菌病例报告及文献综述

Mycobacterium thermoresistibile: case report of a rarely isolated mycobacterium from Europe and review of literature.

作者信息

Neonakis I K, Gitti Z, Kontos F, Baritaki S, Petinaki E, Baritaki M, Zerva L, Spandidos D A

机构信息

Mycobacteriology Laboratory, Department of Clinical Bacteriology, Parasitology, Zoonoses and Geographical Medicine, University Hospital of Heraklion, Heraklion, Greece.

出版信息

Indian J Med Microbiol. 2009 Jul-Sep;27(3):264-7. doi: 10.4103/0255-0857.53214.

Abstract

Mycobacterium thermoresistibile is a non-tuberculous mycobacterium strongly associated with human infections. Since 1966, there have only been six reports of its isolation from clinical samples. We report on the first case from Europe and review all the previous cases. Identification was achieved with sequencing of the 16S rRNA and hsp65 genes. This study presents its phenotypic and biochemical profile, susceptibilities to selected antibiotics and hsp65 polymerase chain reaction-restriction fragment length polymorphism profile with BsteII and Hae III .

摘要

耐热分枝杆菌是一种与人类感染密切相关的非结核分枝杆菌。自1966年以来,从临床样本中分离出该菌的报告仅有6例。我们报告了欧洲的首例病例,并对之前所有病例进行了回顾。通过对16S rRNA和hsp65基因进行测序实现了鉴定。本研究展示了其表型和生化特征、对所选抗生素的敏感性以及用BsteII和Hae III进行的hsp65聚合酶链反应-限制性片段长度多态性图谱。

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