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通过对在美国收集的临床分离株进行rpoB测序鉴定出一种新出现的病原体——马赛分枝杆菌。

Identification of an emerging pathogen, Mycobacterium massiliense, by rpoB sequencing of clinical isolates collected in the United States.

作者信息

Simmon Keith E, Pounder June I, Greene John N, Walsh Frank, Anderson Clint M, Cohen Samuel, Petti Cathy A

机构信息

Associated Regional and University Pathologists (ARUP) Instititue for Clincal and Experimental Pathology, Salt Lake City, UT 84108, USA.

出版信息

J Clin Microbiol. 2007 Jun;45(6):1978-80. doi: 10.1128/JCM.00563-07. Epub 2007 Apr 4.

DOI:10.1128/JCM.00563-07
PMID:17409204
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1933107/
Abstract

Mycobacterium massiliense is a rapidly growing mycobacterium that is indistinguishable from Mycobacterium chelonae/M. abscessus by partial 16S rRNA gene sequencing. We sequenced rpoB, sodA, and hsp65 genes from isolates previously identified as being M. chelonae/M. abscessus and identified M. massiliense from isolates from two patients with invasive disease representing the first reported cases in the United States.

摘要

马赛分枝杆菌是一种快速生长的分枝杆菌，通过部分16S rRNA基因测序，它与龟分枝杆菌/脓肿分枝杆菌无法区分。我们对先前鉴定为龟分枝杆菌/脓肿分枝杆菌的分离株的rpoB、sodA和hsp65基因进行了测序，并从两名患有侵袭性疾病患者的分离株中鉴定出马赛分枝杆菌，这是美国首次报告的病例。

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