Infectious Diseases Section, Veterans Affairs New Jersey Health Care System, East Orange, NJ, USA.
AIDS. 2009 Sep 10;23(14):1911-3. doi: 10.1097/QAD.0b013e32832f3c65.
We reviewed the effect of adding maraviroc on CD4 cell counts in nine patients on antiretroviral therapy with full viral suppression but impaired CD4 cell recovery. There were no significant differences in changes in CD4 cell count, percentage of CD4 cells, or in the ratio of CD4/CD8 cells at 30 days and 25 weeks of maraviroc therapy. Plasma endotoxin levels measured in four patients before and during maraviroc treatment also showed no significant differences.
我们回顾了在 9 名接受抗逆转录病毒治疗且病毒完全抑制但 CD4 细胞恢复受损的患者中添加马拉维若对 CD4 细胞计数的影响。在马拉维若治疗 30 天和 25 周时,CD4 细胞计数、CD4 细胞百分比或 CD4/CD8 细胞比值的变化均无显著差异。在 4 名患者中测量的血浆内毒素水平在马拉维若治疗前后也没有显著差异。