Grosso Mariano, Imran Muhammad Babar, Volterrani Duccio, Roncella Manuela, Abufalgha Khalid, Grassetto Gaia, Al-Nahhas Adil, Rubello Domenico, Mariani Giuliano
Regional Cetre of Nuclear Medicine, University Hospital of Pisa, Pisa, Italy.
Nucl Med Rev Cent East Eur. 2008;11(2):70-2.
In breast cancer, neoadjuvant chemotherapy needs early indication for responsiveness. Tc-99m sestamibi scintimammography provides comprehensive information about the extent of disease including multiple foci in one or both breasts and possible involvement of nodes. In the present case, X-mammography was positive for a suspicious mass in the upper quadrant of the left breast only. On the other hand,Tc-99m Sestamibi scintimammography was able to depict the full extent of the disease, including its spread to the axillary lymph node, and gave useful information on the effectiveness of neoadjuvant chemotherapy. The case reported here demonstrates that Tc-99m sestamibi scintimammography was useful in detecting bilateral breast cancer and could provide additional information on possible axillary lymph node involvement. Furthermore, Tc-99m sestamibi scintimammography was effective in monitoring response to chemotherapy in the studied case.
在乳腺癌中，新辅助化疗需要早期判断反应性。锝-99m 甲氧基异丁基异腈乳腺闪烁显像能提供有关疾病范围的全面信息，包括一侧或双侧乳房中的多个病灶以及可能的淋巴结受累情况。在本病例中，X线乳房造影仅显示左乳上象限有一个可疑肿块呈阳性。另一方面，锝-99m 甲氧基异丁基异腈乳腺闪烁显像能够描绘出疾病的全貌，包括其向腋窝淋巴结的扩散，并提供了有关新辅助化疗效果的有用信息。此处报告的病例表明，锝-99m 甲氧基异丁基异腈乳腺闪烁显像在检测双侧乳腺癌方面很有用，并且可以提供有关可能的腋窝淋巴结受累的额外信息。此外，在该研究病例中，锝-99m 甲氧基异丁基异腈乳腺闪烁显像在监测化疗反应方面是有效的。
