Bielajew C H, Harris T
School of Psychology, University of Ottawa, Ontario, Canada.
J Psychiatry Neurosci. 1991 Sep;16(3):109-14.
In the past decade, there has been considerable emphasis on developing and refining the measurement instruments used to assess the rewarding effect of brain stimulation. These efforts have given rise to quantitative methods aimed at revealing the underlying neurophysiology and neuroanatomy by tracing the trajectories of the relevant neurons. In this paper, we summarize some of the quantitative findings that have resulted from research at the University of Ottawa in the neurobiology of motivated behavior. These include studies using markers to reveal which structures are metabolically activated by rewarding brain stimulation, comprehensive mapping of brain areas for self-stimulation and other stimulation-induced behaviors, and examination of the effects of benzodiazepines on feeding and reward.
在过去十年中，人们相当重视开发和完善用于评估脑刺激奖赏效应的测量工具。这些努力催生了旨在通过追踪相关神经元轨迹来揭示潜在神经生理学和神经解剖学的定量方法。在本文中，我们总结了渥太华大学在动机行为神经生物学研究中得出的一些定量研究结果。这些研究包括使用标记物来揭示哪些结构因奖赏性脑刺激而发生代谢激活、对自我刺激及其他刺激诱发行为的脑区进行全面图谱绘制，以及研究苯二氮䓬类药物对进食和奖赏的影响。
