Corbett D, Laferriere A, Milner P M
Physiol Behav. 1982 Mar;28(3):531-4. doi: 10.1016/0031-9384(82)90151-2.
Prior electrical stimulation of the medial prefrontal cortex MFC facilitated the subsequent acquisition of intracranial self-stimulation (ICSS) from the same MFC electrode site. Stimulations that were spaced over a period of six days were more effective in producing this facilitation than the same number of stimulations delivered over a two day period. These data suggest that the rewarding effects of MFC stimulation may involve some process akin to the kindling phenomenon and as such may provide insights in the neuronal modifications thought to underlie learning and memory.
先前对内侧前额叶皮质（MFC）进行电刺激促进了随后从同一MFC电极部位获取颅内自我刺激（ICSS）。在六天时间内间隔进行的刺激比在两天时间内进行相同次数的刺激在产生这种促进作用方面更有效。这些数据表明，MFC刺激的奖赏效应可能涉及某种类似于点燃现象的过程，因此可能为被认为是学习和记忆基础的神经元修饰提供见解。
